Las glándulas suprarrenales, ubicadas encima de los riñones, producen hormonas esenciales para el funcionamiento del cuerpo. La capa. CAPÍTULO Trastornos de la corteza suprarrenal La corteza suprarrenal externa secreta una diversidad de hormonas Hiperfunción de la médula. Es una operación en la cual se extirpan una o ambas glándulas suprarrenales. Estas glándulas son parte del sistema endocrino y están.

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The Spanish Association of Pediatrics has as one of its main objectives the dissemination of rigorous and updated scientific information on the different areas of pediatrics. Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate.

The magazine, referring to the Spanish-speaking pediatric, indexed in major international databases: The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. CiteScore measures average citations received per document published. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact.

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SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Se presentan 4 pacientes diagnosticados de enfermedad de Cushing en un hospital terciario, desde enero de a diciembre del El cortisol libre urinario estaba elevado en los 4 pacientes. Dos de los 4 pacientes presentan hipopituitarismo secundario. Cushing’s disease is uncommon in childhood.


It is usually caused by the oversecretion of adrenocorticotrophic hormone ACTH by a pituitary corticotroph adenoma. Clinical abnormality is often undetected for long periods of time. The principal clinical features are growth retardation and obesity. We present four patients who were diagnosed with Cushing’s disease in a tertiary hospital from January to December There were two boys and two girls, aged years.

The main clinical features at presentation were growth failure and excessive weight gain. The interval between onset of symptoms and diagnosis ranged from 2. All patients presented moon face and increased fat around the neck. Pituitary microadenoma was detected by magnetic resonance imaging in three patients; no tumor was detected in the fourth patient and inferior petrosal sinus sampling was performed, showing left lateralization of ACTH central secretion.

Therapy consisted of transsphenoidal surgery in all patients. Two patients are in remission, one patient presented disease recurrence requiring total hypophysectomy because the tumor could not be completely removed and one patient had persistent disease after a second intervention and required pituitary radiotherapy.

Two patients showed pituitary hormone deficiency after therapy. Previous article Next article. Diagnosis, treatment and long-term outcome in cushing’s disease.

Monforte de Lemos, Hospital Universitario La Paz. This item has received.

Dos de los 4 pacientes presentan hipopituitarismo secundario. Two patients showed pituitary hormone deficiency after therapy. Full text is only aviable in PDF. N Engl J Med,pp. Cushing’s Disease in childhood: Presentation, investigation, treatment and long-term outcome.

Trastornos de la corteza suprarrenal | Fisiopatología de la enfermedad, 7e | McGraw-Hill Medical

Horm Res, 55pp. Investigation, management and therapeutic outcome in 12 cases of childhood and adolescent Cushing’s Syndrome.


Clin Endocrinol, 43pp. Relative contributions of inferior petrosal sinus sampling and pituitary imaging in the investigation of children and adolescents with ACTH-dependent Cushing’s Syndrome. J Clin Endocrinol Metab, 86pp. Van der Lely, W. Transsphenoidal selective adenomectomy is the treatment of choice in patients with Cushing’s disease.

Considerations concerning preoperative medical treatment and huperfuncion long-term follow-up. J Clin Endocrinol Metab, 80pp.

Treatment, and retreatment, of Cushing’s disease. Horm Res, 58pp. The long term outcome of pituitary irradiation after unsuccessful transsphenoidal surgery in Cushing’s Disease. Subscribe to our Newsletter.

Extirpación de las glándulas suprarrenales

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